User Recommendations for The Melancholy of Haruhi Suzumiya

In The Melancholy of Haruhi Suzumiya and Shakugan no Shana, a normal boy (Yuji and Kyon) is thrown into a completely abnormal world when they meet a girl with special powers (Haruhi and Shana). They both have elements of action, comedy, and romance; with Shana more on the action side and Haruhi Suzumiya more on the comedy side.

Both of these shows similarly combine the "school life" and "sci-fi" genres in order to create a very interesting overall feel. As an added bonus, character designs for both series were done by the same amazing Ms. Noizi Ito, so you're sure to enjoy the familiar style.