Eyeshield 21 is the best Anime/Manga about sports, it is about a kid named Kobayakawa Sena who discovers the awesome world of American Football or Football as an american like myself would call it. To be honest,ES21 was my first sports anime and it is the one that hooked me to sports anime. it is really funny and whenever i have a bad day, i watch one ep of it and i cheer up. It combines both comedy and sports together to make the best sports Anime/Manga