Yozakura Quartet is focused on a consultation office of demons and humans in a consultation office who exist to protect a town where demons and humans coexist against evil demonic threats, this series dealing with evil demon Enjun trying to unleash the evil demons that have been sealed by the group. Many of the episodes in the first half of the series serve to introduce the members of the consultation office, their backgrounds before the start of the series and their regular duties throughout the town. They are fleshed out enough where you could care for them as characters, but these episodes lack much inthe way of intrigue or tension beyond hints of Enjun's incoming arrival as they are mostly light-hearted and sort of follow a slice-of-life style plot.

The second half of the series is where things pick up in Yozakura's storytelling when Enjun makes his presence felt on the town and the effects of his actions effect the populace. An added twist to the developments come from a revelation where Enjun is possessing the body of someone close to several members of the consultation office that add some interesting tension into the series as these characters feel conflicted over how to approach the situation throughout much of the show's second half. While the storyline does go for a black-and-white moral approach, Enjun does get enough dimension to his character to show how manipulative his character can be with the body he possesses and the strong belief that he has for his actions in trying to free the demons that were sealed.

Even with the solid second half though, Yozakura Quartet does have its issues. I questioned the point of the land gods' presence in this series as they couldn't do anything to assist the consultation group due to "rules" they had to follow and they didn't get much in the way of depth. Enjun's partner in his plans also lacks much in the way of dimension and depth beyond serving as major obstacle in the efforts of the consultation group to halt Enjun's plans and the series fails to explain how Enjun was freed from being sealed. Also, the ending for this felt a bit too anti-climatic considering how difficult it was for the group to deal with Enjun throughout of the course of the series beyond overcoming their hesitance at taking him down.

The visual presentation to this series is rather average with bright colors and solid, though rough, levels of detail implemented in the designs of characters and scenery, though nowhere as visually impressive as TV titles like Code Geass R2 and Ga-Rei: Zero that aired that year. Action scenes normally make use of reused frames and speed stripes as shortcuts, making them not so impressive despite the unique abilities that several characters in this series have.

Overall, Yozakura Quartet is a somewhat solid series that does flesh out the members of the consultation agency enough where you know of their characters and backgrounds and has an engaging second half coming from the group's efforts to thwart Enjun's plans. However, the series does suffer in that it doesn't bother to flesh out some major aspects to its plot and the questionable relevance of some characters even being in the series. It's not a masterpiece by any means, but still worth a look if you're looking for something that can be quickly breezed through.