Basically, the plot is about the relationship between a teacher (Takahashi, Tetsuo) and his students who happen to be a minority of supernatural beings called ajin or “demi”. It also happens by chance that he is a biologist, really interested in studying the demi from a scientific point of view to demystify the legends that revolve around them. As he learns more about the demis and works with them to help them deal with the unique challenges they face due to their physical and social differences, Takahashi also reflects on his own life and relationships. The story addresses interesting themes such as acceptance, prejudice, and compassion, anduses the supernatural genre to explore issues relevant to real life. In addition to the plot, Petosu's art is colorful and expressive, helping to bring the characters and their environments to life, although it should be noted that his backgrounds are not very elaborate and the plot sometimes commits the sin of taking itself too seriously.
If you like stories that revolve around the student-teacher relationship and also where a good influence is reciprocal, I recommend that you read this manga.